High Resolution Mass determination, separation, qualitative and quantitative analysis by liquid chromatography Mass spectroscopy LC(UV)MS/MS using Agilent 6520 QTOF analyzer. High-resolution LCMS/MS Quadruple Time of Flight is an identification tool which allows distinguishing peaks separated by only small m/z values and provides excellent mass accuracy < 2ppm for MS and < 4 ppm for MS/MS also allows selective detection of desired compounds in the presence of interferences. Liquid Chromatography Mass Spectrometry enables chromatographic separation, identification and quantification of compounds in a wide range of masses (50-20000). Ionization of the samples occurs in Dual Electro Spray Ionization source which is suitable for compounds that can have a charge induced and for multiply charged compounds such as: proteins, peptides, oligonucleotides. The samples for this analyzer have to be soluble in polar well vaporizable solvents.

Q-TOF LC/MS

Mass Determination by Gas Chromatography/Mass Selective Detector (GC/MSD) and Qualitative analysis using Agilent 5977B Series GC/MSD:  The 5977B High Efficiency Source (HES) GC/MSD is the most trusted single-quadrupole GC/MS system providing lowest Instrument Detection Limit (IDL) as low as 1.5 fg IDL and best S/N.  The ultra-efficient EI source maximizes the number of ions that are created and transferred out of the source body and into the quadrupole analyzer.

The solvents used for this GC/MSD should be non-polar vaporable solvents. The mass detection is up to m/z=600.